The effects of mesotherapy become apparent within a week of the first session. Even immediately after the session, the patient feels a sense of revitalization and fullness in their skin. This, of course, depends on the severity of the existing deformity. While results are much faster in a younger patient, it's inevitable that results may take a bit longer in an older patient with more sagging tissue. Mesotherapy has different mechanisms of action. The effects vary depending on the molecular structures used. If you want skin tightening and increased tone, you'll need a different product. If you want to slightly lift sagging tissue, you can use a different product. There are fillers available for use in these sagging areas of the face.